Melatonin Zn Se tablets have been developed by the world melatonin expert Walter Pierpaoli, M.D.

This product expresses the best imaginable melatonin preparation now available as a food additive and dietary supplement to anybody wanting to take advantage of the extraordinary scientific observations of Dr. Walter Pierpaoli MD and his co-workers, authors of all the scientific work described in the New York Times bestseller “The Melatonin Miracle”, (Simon & Schuster, New York), now translated into 17 different languages.

The basic experimental findings of 35 years described in the book, which resulted in the discovery of the existence of a programmed “Aging Clock” in the pineal gland complex of the brain, has been relentlessly continued in order to further improve the anti-aging activity of circadian, night melatonin.

Dr. Pierpaoli investigated the possible mechanisms and also the molecules which cooperate and synergize with melatonin in the regulation and re-synchronization of fundamental immunological and hormonal functions which are lost or deranged in the course of aging.

Melatonin Zn Se is more than “just” melatonin

Dr. Pierpaoli has carefully designed his product to give it a number of benefits over “plain regular” melatonin. For example, during recent studies and long-term experiments with old rodents, it has been observed that zinc can correct completely aging-dependent immunodepression and several other hormonal and metabolic alterations typical of aging. It has been found that the low zinc levels in aging animals can be restored to normal values with nocturnal administration of melatonin or transplantation of the pineal gland from young into older animals.

Zinc is an essential component of more than 200 enzymes and one of the most relevant trace elements in the body. 8,9 It is thus clear that additional zinc must be supplemented daily to the body of an aging organism with a low zinc balance, in order that melatonin can better exert its anti-aging activities on the entire neuroendocrine and immune systems! This important and novel scientific observation of the powerful anti-aging and immuno-enhancing activity of the combination of zinc and melatonin has now resulted into the development of Melatonin Zn Se.

Also as selenium is a fundamental trace element of the body and possesses powerful anti-cancer effects and as modern agriculture and alimentary habits have dramatically decreased the daily input of selenium from the diet, selenium is also included in Melatonin Zn Se. Selenium is essential for the enzymatic reaction responsible for the synthesis of glutathione, a powerful physiological molecule which constantly protects the body from oxidative damage.

A lack of selenium will thus result into a loss of the detoxification capacity of the body, immunodepression and onset of degenerative diseases and cancer.

This is the reason why Melatonin Zn Se combines, in a unique synergistic combination, three fundamental anti-aging molecules.

The natural night peak

In addition, a very special feature of Dr. Pierpaoli’s product is its ability to release melatonin in the same way as the natural release takes place from the brain’s pineal gland. In other words, Melatonin Zn Se mimics nature by producing a night peak release of melatonin in the same way as is normal in youth. Normal and especially sublingual and time-released versions of melatonin are unable to do this, only Dr. Pierpaoli’s Melatonin Zn Se has been designed, tried and tested for this purpose.

So whilst melatonin plays the master role for reactivation and restoration of its natural night peak to juvenile levels, (thus resulting into normalization of all measurable immunological and endocrine functions in the course of aging). The positive aging-postponing, metabolic and immunological effects of Melatonin Zn Se can be easily measured by anybody by means of a normal periodic check-up.

These restoring metabolic changes will become progressively more visible and remarkable in the course of use after initiation of the treatment with Melatonin Zn Se.

Indeed clinical trials using Dr. Pierpaoli’s melatonin have supported its efficacy for:

Melatonin Zn Se®

Dr. Walter Pierpaoli himself has created the world’s finest melatonin supplement- Melatonin Zn Se. Not only does it contain pharmaceutical grade melatonin, but the combination with zinc and selenium and its unique night-peak release system adds synergistic benefits that are not available with other brands.

If you want the best, choose Melatonin Zn Se the only melatonin supplement recommended by the world’s number one melatonin expert- Dr. Walter Pierpaoli.

Active ingredients in each tablet:

• Melatonin (N-acetyl-5-methoxytryptamine), 3mg, synthetic, certified purity: (99.9 % (HPLC)
• Zinc-orotate x 2H2O, 50mg corresponding to 8.7mg zinc
• Selenium, 50mcg, from sodium selenite pentahydrate

Melatonin Zn Se® is produced in Italy in compliance with the severe international rules of Good Manufacturing Practise (cGMP).

Dosage:

30 to 39 years of age: 1.5mg at bedtime.
40 to 49 years of age: 1.5mg to 3mg at bedtime.
50 to 74 years of age: 3mg at bedtime.
Above 75 years of age: 3mg to 6mg at bedtime.

Important notes:

Whilst melatonin has not shown any toxicity in studies, we do not recommend that this product should be given to healthy children, pregnant women and lactating mothers unless specifically prescribed by a physician.

Order today

120x 3mg tablets, (a 4-month supply for the average person) costs as little as £39.99 (Pounds Sterling) and includes taxes in the EU as well as shipping and handling charges to anyplace in the world.

Payment

1. Use our online order form by clicking here and pay via Google Checkout.

2. Phone us in the UK (Monday-Friday 10am to 6pm GMT) on +44 (0)208 181 6105 if the line is busy there is a voicemail option we WILL CALL YOU BACK. We accept payment by credit card, (we accept Visa, MasterCard, Switch, Delta and JCB).

3. Send us a cheque, (made out in Pounds Sterling and payable at a British bank) to the address below.

Contact details:

For further information about our wholesale programs please contact one of our customer service agents at the following:

Phone: +44 208 123 2106
Fax: +44 208 181 6105
e-mail: info@melatoninznse.com

Note: S&H worldwide and EU taxes are included, please allow 21-days for delivery. Restrictions may apply in some countries and all orders are subject to IAS terms and conditions.

1. Pierpaoli, W. and Regelson W. with Carol Colman, “The Melatonin Miracle”, Simon & Schuster, New York, 1995.
2. Pierpaoli, W. The pineal gland: a circadian or a seasonal aging clock? Aging 3: 99-101, 1991.
3. Pierpaoli, W. Dall’Ara, A, Pedrinis, E. and Regelson, W. The pineal control of aging. The effects of melatonin and pineal grafting on the survival of older mice. Second Stromboli Conference on Aging and Cancer, June 1990. Ann. N.Y. Acad. Sci. 621: 291-313, 1991.
4. Pierpaoli, W., and Lesnikov, V.A. The pineal aging clock. Evidence, models, mechanisms, interventions. The Aging Clock. Third Stromboli Conference on Aging and Cancer, June 1993. Ann. N.Y. Acad. Sci. 719: 461-473, 1994.
5. Pierpaoli, W. and Regelson, W. Pineal control of aging: effect of melatonin and pineal grafting on aging mice. Proc. Natl. Acad. Sci. USA, 94: 787-791, 1994.
6. Mocchegiani, E., Bulian, D., Santarelli, L., Tibaldi, A., Muzzioli, M., Pierpaoli, W. and Fabris, N. The immuno-reconstituting effect of melatonin or pineal grafting and its relation to zinc pool in aging mice. J. Neuroimmunol. 53: 189-201, 1994.
7. Mocchegiani, E., Bulian, D., Santarelli, L., Tibaldi, A., Muzzioli, M., Lesnikov, V., Pierpaoli, W. and Fabris, N. The zinc pool is involved in the immunoreconstituting effect of melatonin in pinealectomized mice. J. Pharmac. & Exp. Therap. 277: 1200-1208, 1996.
8. Mocchegiani, E., Bulian, D., Santarelli, L., Tibaldi, A., Pierpaoli, W. and Fabris, N. The zinc-melatonin interrelationship. A working hypothesis. The Aging Clock. Third Stromboli Conference on Aging and Cancer, June 1993. Ann. N.Y. Acad. Sci. 719: 298-307. 1994.
9. Fabris, N. Neuroendocrine-immune aging: an integrative view on the role of zinc. The Aging Clock. Third Stromboli Conference on Aging and Cancer, June 1993. Ann. N.Y. Acad. Sci.719: 353-368, 1994.
10. Meister, A. and Anderson, M.E. Glutathione. Ann. Rev. Biochem. 52: 711-760, 1983.